|Titre :||Detecting, Studying, and Treating Autism Early: The One-Year Well-Baby Check-Up Approach (2011)|
|Auteurs :||Karen PIERCE|
|Type de document :||Article : Texte imprimé et/ou numérique|
|Dans :||The journal of pediatrics (n°159(3), 2011)|
|Article en page(s) :||p.458-465.e6|
|Index. décimale :||AUT.40 (Dépistage, diagnostic et évaluation)|
Objectives To determine the feasibility of implementing a broadband screen at the 1-year check-up to detect cases of autism spectrum disorders (ASD), language delay (LD), and developmental delay (DD).
Study design The Communication and Symbolic Behavior Scales Developmental Profile Infant-Toddler Checklist was distributed at every 1-year pediatric check-up; 137 pediatricians and 225 infants participated. Screens were scored immediately, and failures referred for further evaluation.
Results Pediatricians screened 10 479 infants at the 1-year check-up; 184 infants who failed the screen were evaluated and tracked. To date, 32 infants received a provisional or final diagnosis of ASD, 56 of LD, nine of DD, and 36 of ''other.'' Five infants who initially tested positive for ASD no longer met criteria at follow-up. The remainder of the sample was false positive results. Positive predictive value was estimated to be .75.
Conclusions The 1-Year Well-Baby Check-Up Approach shows promise as a simple mechanism to detect cases of ASD, LD, and DD at 1 year. This procedure offers an alternative to the baby sibling design as a mechanism to
study autism prospectively, the results of which will enrich our understanding of autism at an early age. (J Pediatr 2011;159:458-65).
|Candidats descripteurs :||ENFANT ; AUTISME ; LANGAGE ; TOUT PETIT ; EVALUATION ; DEPISTAGE PRECOCE|